Estimated glomerular filtration rate function in patients with and without metabolic syndrome

María E Lizardo, María del Pilar Navarro, Marqjuly Camacho, Melvimar Alejandra Magallanes-Hernández, Rubsy Gabriela Pacheco-Gutiérrez, Mariela López-Bordones, Román Cabello, Gregoria González-Mayo, Hember Vicci, Luis Dorta

Abstract


Introduction: Metabolic syndrome (MS) is an independent risk factor, which affects the development of chronic kidney disease, so the glomerular filtration rate (GFR) as an indicator of glomerular function in patients with and without MS who attended the outpatient clinic “los Grillitos, sector Caña de Azucar”. Materials and Methods: A comparative, correlational, cross-sectional study was conducted in a non-probability sample of convenience consisting of 60 patients with MS diagnosed according to the criteria Panel ATP III, and 60 apparently healthy individuals, whom the GFR was determined by the Cockcroft-Gault as well as clinical and biochemical parameters for the diagnosis of MS. Results: Out of the total patients evaluated, 37 (30.7%) showed alterations that put them in grades G2 and G3 system risk stratification of CKD, of these 18 and 19 corresponded to patients with and without MS respectively. Glomerular Hyperfiltration (> 120 mil / min) it was found in both groups 28 (46.7%) and 24 (40%) cases of patients with and without MS respectively. The glomerular function was strongly correlated with abdominal obesity and high levels of stress arterial. As for the number of criteria and its relationship to the level of kidney damage present, not a firm to increase the latter with respect to the first (p=0.385) trend was observed. Conclusion: The change in the glomerular function is not directly related to the MS but with its components, specifically abdominal obesity and hypertension.


Keywords


Metabolic syndrome x; glomerular filtration rate; obesity; hypertension; renal insufficiency, chronic



DOI: http://dx.doi.org/10.20320/rfcsudes.v3i1.102

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